Neuroimmunology

Research Interests: My lab studies the olfactory neuroepithelium as an immune barrier and its involvement in neurodegenerative disease pathogenesis.

Research Interests: Dr. Toedebusch is a veterinary neurologist and comparative neuro-oncologist dedicated to improving the lives of humans and dogs with brain tumors. She combines her clinical expertise and scientific training to 1) advance understanding of the translational relevance of spontaneously occurring high-grade glioma as a model for human disease and 2) Uncover the molecular mechanisms of immunosuppression in high-grade glioma. Dr. Toedebusch collaborates with a multidisciplinary team of scientists and physicians to develop and test innovative therapies through clinical trials in canine patients. Her ultimate goal is to discover new treatments for brain tumors that benefit both dogs and humans—advancing care and quality of life across species.

Research Interests: My research is focused on clinical immunology, neuroimmunology and autoimmunity. The current projects include the immunobiology of neurodevelopmental disorders including autism and schizophrenia. We are also interested in the maternal gestational immune environment and how dysregulation of the maternal immune system impacts offspring development.

Research Interests: My research centers on central nervous system glial development and glial diseases.

Research Interests: Cancer immunotherapy, viral immunology, preclinical modeling.

Research Interests: Focusing on how bidirectional communication between the nervous and immune system alters immune outcomes in gut and lung.

Research Interests: Wound healing, CNS inflammation

Research Interests: My lab studies the development of the microbiota-gut-brain axis. We are interested in understanding the mechanisms of communication between the gut and brain, including the specific neuro, immune, and endocrine pathways involved.

Research Interests: My research focuses on neuro-immune interactions at the blood-brain barrier (BBB) as a relevant contributor to neuroinflammation and consequent neurodegeneration. My long-term goal is to contribute to the identification of non-immunosuppressive and sex-specific therapeutic targets, specifically by elucidating 1) triggering factors of BBB dysfunction, 2) their role in neuropathogenesis and neuroinflammation, and 3) their association with sex-biased autoimmune disorders (e.g. multiple sclerosis).

Research Interests: Evaluating the immune response in children with autism and to examine the interface between the immune system and the central nervous system.