Immuno-therapy

My research interests are primarily in adoptive T-cell therapy (ACT) for solid tumors. While ACT has demonstrated impressive results in hematologic malignancies, success has been limited in solid tumors. I am investigating ways to improve ACT through novel methods of generating genetically-modified cells and through modulating the tumor immune microenvironment.

Research Interests: Research in the Zamora Lab focuses on cancer immunology, with an emphasis on developing strategies to modulate the immune system for more precise and effective elimination of cancer cells. We employ cellular engineering techniques to enhance immune cell specificity while minimizing off-target toxicities. Our work integrates advanced single-cell technologies to profile the phenotypic, functional, and receptor repertoires of neoantigen-specific T cells.