Adaptive Immunity

Research Interests: My research is focused on immunological hurdles in regenerative medicine. Specifically, my lab has determined that some cells may not be immunoprivileged, as previously prescribed by a well-accepted dogma. Hence, my team is assessing the relevance of MHC-I matching in stem cell therapy and musculoskeletal transplantation.

Research Interests: Research Interests: mechanistic understanding of inflammation in chronic diseases; specifically understanding the innate and adaptive immune response in diabetic kidney disease (DKD), and characterizing the role of the immune response on DKD pathogenesis. First group to identify an association between urine complement components and progression of diabetic kidney disease (DKD).

Research Interests: HIV immunopathology

Research interests: Our laboratory focuses on the design and application of antibodies and CARs in improving Cancer immunotherapy. We are also interested in identifying regulatory mechanisms in the Cancer-Tumor microenvironment that could interfere with the efficacy of T-cell-based immunotherapy.

Research Interests: Improvement of cancer immunotherapy and development of cancer vaccines.

Research Interests: Cancer immunotherapy, viral immunology, preclinical modeling.

Research Interests: T cell responses to Salmonella and Chlamydia

Research Interests: Focusing on how bidirectional communication between the nervous and immune system alters immune outcomes in gut and lung.

Research Interests: Antibody production requires B cell maturation coordinated by changes in transcriptional and post-transcriptional mechanisms of gene expression. The lab studies the transcription factors and RNA binding proteins that drive maturation into antibody secreting plasma cells.

Research Interests: My lab focuses mainly on mucosal immunity in chronic HIV infection, with an emphasis on the gastrointestinal and reproductive tracts. Topics of interest include tissue-resident T-cells, regulatory T-cells (Treg), mucosa-associated invariant T-cells (MAIT) and the contributions of these cell types to host defense against mucosal pathogens.