Alan Lombard, PhD

Research Interests: My research centers on the study of prostate cancer and mechanisms underlying its progression and both response and resistance to therapy. The lab's current focus is on the integration of PARP inhibitor treatment strategies into clinical care and the design of novel combination therapies which will enhance PARP inhibitor efficacy. Specific interests include studies to understand treatment induced senescence and how we may target senescent cells within the tumor microenvironment using rationally selected senolytic drugs. We are additionally interested in understanding the immune landscape of prostate tumors and how to develop novel strategies to utilize immunotherapies for aggressive disease.