Tom Ambrosi, PhD

Research Interests: Our lab studies the interactions of skeletal and hematopoietic cellular lineages in postnatal bones of mice and humans using a stem cell-centric approach. Interrogating skeletal stem cell biology during development, aging and cancer/disease allows us to dissect the cellular niches and molecular signals maintaining hematopoietic stem cells and regulating immune cell output. Our long-term goal is to leverage our discoveries to develop strategies to prevent and target skeletal stem cell-based bone aging and hematopoietic malignancies.